Diponegoro University established Department of Biology in 1975. The unit is a consolidation of biology field from the various biology based faculty, such as the Faculty of Medicine and the Faculty of Animal Husbandry and Fishery. Department of Biology has a role as a facilitator for teaching and practice of biology course in the biology based faculty. In accordance with the Master Plan Development (RIP) of Diponegoro University at that time, the Department of Biology developed as Division of Biology, Faculty of Mathematics and Natural Sciences.
Implementation of planning the establishment of Faculty of Mathematics and Natural Sciences started in 1987, and in the academic year 1988 Diponegoro University had open 3 new courses, namely: Biology, Chemistry, and Physics. Division of Mathematics structurally still under the Faculty of Engineering. Operational management to the four Study Program (Mathematics, Biology, Chemistry, and Physics) conducted by Board of Management MIPA (BP-MIPA), based on decree The Rector of the University No. 63/SK/PT09/1988.
Based on the decree Minister of Education and Culture No. 0369/O/1993, Faculty of Mathematics and Natural Sciences (MIPA) was officially established at the Diponegoro University. Legality of Biology Study Program supported by the decree ofÂ Minister of Education and Culture No. 220/DIKTI/Kep/1996. Since that time Biology Study Program develop internal organization and management in order to increase quality.